Most of this is itch control. The page that matters is the anaphylaxis one, and it is not about plants at all.
Ordinary insect bites and stings are an itch and a swelling problem, with one exception that is a life-threatening emergency.
Itch control, in order. A cold pack; an oral antihistamine (a second-generation one in the daytime, a sedating one at night); a topical corticosteroid for a large local reaction; and calamine or a plain moisturiser. Do not scratch — scratching breaks the skin and secondary bacterial infection is the main complication of a bite.
Plantain and other demulcent, astringent leaves are the traditional bite remedy and are harmless: a crushed leaf held on the bite, or a cooled infusion on a cloth. The evidence is modest and the harm is nil.
Bee and wasp stings. Scrape the sting out sideways with a fingernail or card (do not squeeze the venom sac), cool the area, and use an antihistamine. A large local reaction — swelling spreading well beyond the sting over 24-48 hours — is uncomfortable and usually not dangerous; it is different from anaphylaxis.
Anaphylaxis is the emergency and it is not a plant problem. Widespread hives, swelling of the lips, tongue or throat, difficulty breathing, wheezing, a feeling of impending doom, dizziness or collapse, after a sting or a food. The treatment is intramuscular adrenaline (epinephrine) from an auto-injector, given immediately, and then emergency services. Antihistamines do not treat anaphylaxis. Anyone with a known risk should carry two auto-injectors and know how to use them, and anyone who has had a reaction should be assessed by an allergist.
Plant contact reactions. Poison ivy, oak and sumac cause an allergic contact dermatitis, not an immediate reaction. The treatment is washing the skin with soap and water within 30 minutes of exposure (the urushiol must be removed before it binds), then cool compresses and topical steroids. The rash is not contagious — the fluid in the blisters contains no urushiol, and the belief that it spreads is because the eruption appears in stages. Severe cases, especially on the face or genitals, need medical treatment.
The bites that are not ordinary bites. A spreading red area around a bite with fever; a bite with a target-shaped rash (possible Lyme disease); a bite that becomes a black eschar (possible a spider or a venomous bite); and any bite in a person who is immunosuppressed.
Meta-Analysis2025The Journal of allergy and clinical immunology
Comparative efficacy and safety of biologics and systemic immunomodulatory treatments for chronic urticaria: Systematic review and network meta-analysis.
Among individuals with chronic urticaria refractory to antihistamines, standard-dose omalizumab and remibrutinib are among the most effective drugs across multiple patient-important outcomes with a favorable safety profile across the studied duration.
PubMed 40663028 ↗
Meta-Analysis2024The journal of allergy and clinical immunology. In practice
Efficacy and Safety of Systemic Corticosteroids for Urticaria: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Systemic corticosteroids for acute urticaria or chronic urticaria exacerbations likely improve urticaria, depending on antihistamine responsiveness, but also likely increase adverse effects in approximately 15% more.
PubMed 38642709 ↗
Meta-Analysis2024BMJ open
Acupuncture for atopic dermatitis: a systematic review and meta-analysis.
Acupuncture might be an effective and safe treatment for atopic dermatitis.
PubMed 39638592 ↗
Meta-Analysis2019The Cochrane database of systematic reviews
Interventions for hand eczema.
Most findings were from single studies with low precision, so they should be interpreted with caution.
PubMed 31025714 ↗
Meta-Analysis2018Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Food-induced fatal anaphylaxis: From epidemiological data to general prevention strategies.
General strategies should include optimization of the classification and coding for anaphylaxis (new ICD 11 anaphylaxis codes), dissemination of international recommendations on the treatment of anaphylaxis, improvement of the prevention in food and catering areas, and dissemination of specific policies for allergic children in schools.
PubMed 30288817 ↗