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Open Source Apothecary At Home

Open Source Apothecary At Home / Skin and wounds

Sun exposure, sunburn and vitamin D

Sunburn is a burn, sunscreen is the evidence-backed skin-cancer prevention, and vitamin D is the reason people give for not using it.

guide

This page exists because "I need the vitamin D" is the most common reason people decline sun protection, and the trade is a poor one.

Sunscreen prevents skin cancer and photoaging, and the evidence is strongest for squamous cell carcinoma and for preventing sunburn and actinic damage. The evidence for melanoma is more mixed but there is a randomised trial showing reduced melanoma incidence with regular sunscreen use in adults. Reapplication matters more than the SPF number: an SPF 30 applied properly outperforms an SPF 50 applied thinly, and most people apply a quarter of the quantity used in the testing.

Vitamin D can be obtained without burning. The amount of sun needed for vitamin D synthesis is small and is not the amount that burns — a few minutes of midday exposure for a fair-skinned person is enough, and for many people at high latitude in winter, none is enough and supplementation is the reliable route. The recommendation is to supplement rather than to burn, because the dose-response for vitamin D from sun is capped by the skin's own regulation while the DNA damage from sunburn is cumulative.

Sunburn is a thermal and radiation burn. Cool it, hydrate, take an anti-inflammatory early, and do not apply benzocaine-containing products (a documented risk of a serious reaction) or greasy ointments while the skin is hot. Blistering sunburn over a large area is a burn and should be treated as one.

The measures with the best evidence. Sunscreen, protective clothing, shade, and avoiding the peak UV hours. Hat and sunglasses for the face and eyes. Never a sunbed — the melanoma risk is established, and the "safe tan" claim does not exist.

Vitamin D supplementation. 600-800 IU daily for adults, more for documented deficiency under supervision. Do not mega-dose, because very high intermittent dosing has been associated with increased falls and fractures.

Medication photosensitivity. Some drugs make the skin much more sun-sensitive: tetracyclines (doxycycline notably), fluoroquinolones, amiodarone, some diuretics, isotretinoin, and St John's wort. Anyone on one of these needs to know, and this list interacts directly with the herbal section of this handbook.

What the studies found

Meta-Analysis2026BMJ (Clinical research ed.)

Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis.

Based on absolute risk reductions and thresholds considered clinically meaningful, this review found little to no benefits from use of calcium, vitamin D, or combined supplementation on the prevention of fractures and falls.
PubMed 42161415 ↗
Meta-Analysis2025The lancet. Diabetes & endocrinology

Vitamin D supplementation to prevent acute respiratory infections: systematic review and meta-analysis of stratified aggregate data.

This updated meta-analysis yielded a similar point estimate for the overall effect of vitamin D supplementation on ARI risk to that obtained previously, but the 95% CI for this effect estimate now includes 1·00, indicating no statistically significant protection.
PubMed 39993397 ↗
Meta-Analysis2025BMC musculoskeletal disorders

The effects of combined calcium and vitamin D supplementation on bone mineral density and fracture risk in postmenopausal women with osteoporosis: a systematic review and meta-analysis of randomized controlled trials.

PURPOSE: This systematic review and meta-analysis assesses the efficacy of combined calcium and vitamin D supplementation on bone mineral density (BMD) and fracture risk among postmenopausal women with osteoporosis.
PubMed 41063100 ↗
Meta-Analysis2024Annals of medicine

Vitamin D supplementation decrease asthma exacerbations in children: a systematic review and meta-analysis of randomized controlled trials.

Vitamin D supplementation can lower the occurrence of exacerbations in children with asthma, along with the improvement of FEV1.
PubMed 39421966 ↗
Meta-Analysis2023The Cochrane database of systematic reviews

Vitamin D for the management of asthma.

In contrast to findings of our previous Cochrane Review on this topic, this updated review does not find evidence to support a role for vitamin D supplementation or its hydroxylated metabolites to reduce risk of asthma exacerbations or improve asthma control.
PubMed 36744416 ↗

Preparation

Sunburn — treat it as a burn

1. Get out of the sun and cool the skin with a lukewarm shower or cool compresses. 2. Drink fluids. 3. An anti-inflammatory early — ibuprofen at the proper dose, or paracetamol 4. A plain moisturiser or aloe gel afterwards 5. Do not apply benzocaine or other topical anaesthetics. Reactions occur. 6. Do not apply greasy ointments while the skin is hot — they trap heat. 7. Blisters: leave them intact; dress them loosely 8. Blistering over a large area, or with dizziness, nausea or fever — treat as a burn and get medical advice

Sunscreen, used properly

  • SPF 30 or higher, and apply a generous amount — most people apply a quarter of the tested quantity
  • Reapply every 2 hours and after swimming or sweating
  • Broad spectrum (UVA and UVB)
  • Apply 15-20 minutes before going out, including on cloudy days

The other measures

  • Protective clothing; a hat with a brim; sunglasses with UV protection
  • Shade, especially between 10am and 4pm
  • Never a sunbed. Melanoma risk is established.

Vitamin D — supplement, do not burn

  • 600-800 IU daily for most adults; 800 IU over 70
  • Higher only for documented deficiency, with a clinician
  • Do not mega-dose — high intermittent doses increased falls and fractures in trials
  • A few minutes of sun for synthesis does not require burning

Drugs that cause photosensitivity

  • Tetracyclines (doxycycline), fluoroquinolones, amiodarone, some diuretics, isotretinoin, and St John's wort
  • Check any new medicine's sun warning

Cautions and interactions

When this is not a self-care problem — get help

Related

Sources

  1. Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis. BMJ (Clinical research ed.) 2026; doi:10.1002/14651858.CD012424.pub2 PubMed 42161415
  2. Vitamin D supplementation to prevent acute respiratory infections: systematic review and meta-analysis of stratified aggregate data. The lancet. Diabetes & endocrinology 2025; doi:10.1002/9781119536604 PubMed 39993397
  3. The effects of combined calcium and vitamin D supplementation on bone mineral density and fracture risk in postmenopausal women with osteoporosis: a systematic review and meta-analysis of randomized controlled trials. BMC musculoskeletal disorders 2025; doi:10.1111/j.1447-0756.2011.01557.x PubMed 41063100
  4. Vitamin D supplementation decrease asthma exacerbations in children: a systematic review and meta-analysis of randomized controlled trials. Annals of medicine 2024; doi:10.1111/j.1365-2567.2011.03482.x PubMed 39421966
  5. Vitamin D for the management of asthma. The Cochrane database of systematic reviews 2023; doi:10.1002/14651858.CD011511.pub2 PubMed 36744416