Free to read · nothing for sale · no ads, no sponsors · funded by donation

Open Source Apothecary At Home

Open Source Apothecary At Home / The herbs

Calendula

The best first garden project in this handbook — a flower for topical use you can grow and use in one season. — Calendula officinalis

remedy
Calendula Calendula officinalis — hand-drawn plate, stylised. Not for identification — use a field guide and verify with a second source before eating any wild plant.

Calendula (Calendula officinalis) is grown almost entirely for its flowers, and almost entirely for topical use: infused oil, salve, cream and compress.

The evidence is for skin, not for swallowing. Calendula preparations have been used in wound and skin-irritation trials, and there is some randomised evidence for topical use in radiation-induced skin reactions, nappy rash and minor wound healing. The mechanism attributed is anti-inflammatory and mildly antimicrobial from the resinous flower constituents.

What it does not do. Calendula is not an antibiotic and is not for infected wounds. It is a soothing topical for intact or cleanly healing skin — which is exactly the niche where a garden herb can genuinely compete.

The preparation that matters is the infused oil. Dry flowers steeped in a carrier oil extract the resinous compounds; that oil is then the base for a salve with beeswax. It is the best first apothecary project because it uses a harvest you can produce in year one and the result is visibly useful.

The shelf-life catch. Infused oils go rancid. Calendula oil lasts 6-12 months refrigerated and must be checked by smell; a rancid oil on skin is worse than no oil.

What the studies found

Meta-Analysis2009The Cochrane database of systematic reviews

Homeopathic medicines for adverse effects of cancer treatments.

This review found preliminary data in support of the efficacy of topical calendula for prophylaxis of acute dermatitis during radiotherapy and Traumeel S mouthwash in the treatment of chemotherapy-induced stomatitis.
PubMed 19370613 ↗
Systematic Review2019Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

A systematic review of Calendula officinalis extract for wound healing.

There is a need for larger, well-designed randomized control trials to assess the effect of calendula on wound healing including complications.
PubMed 31145533 ↗
Systematic Review2006Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

The prevention and management of acute skin reactions related to radiation therapy: a systematic review and practice guideline.

Skin washing, including gentle washing with water alone with or without mild soap, should be permitted in patients receiving radiation therapy to prevent acute skin reaction.
PubMed 16758176 ↗
Randomized Controlled Trial2025Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Bao Yuan Gao vs. Calendula cream for radiotherapy-induced skin toxicity in head and neck cancer: A randomized controlled trial.

Bao Yuan Gao yielded measurable skin-protective effects, suggesting potential benefits beyond Calendula.
PubMed 40480289 ↗
Randomized Controlled Trial2021The Australasian journal of dermatology

Efficacy of topical Calendula officinalis on prevalence of radiation-induced dermatitis: A randomised controlled trial.

This randomised controlled trial showed no difference between Calendula and standard of care (Sorbolene) for the prevention of radiation-induced dermatitis.
PubMed 32965030 ↗

Growing it

| | | |---|---| | Life | Annual; reliably self-seeds | | Sowing | Direct-sow after last frost, or start indoors | | Light | Full sun; tolerates part shade | | Soil | Any reasonable soil; not fussy | | Spacing | 30 cm | | Harvest | Open flowers, daily at peak | | First harvest | 8-10 weeks from sowing | | Dry | Shade, ambient, on a screen |

Harvest daily — flowers left on the plant set seed and stop producing. Dry whole flowers until crisp, then strip the petals for oil. Save seed from your best plants.

Preparation

Infused oil (the main preparation) — dried flowers covered with a carrier oil (olive, sunflower or jojoba), warmed gently at 40-60 C for 2-4 hours or left 2-6 weeks in a warm dark place. Strain through cloth, press the flowers, bottle in dark glass. 6-12 months refrigerated.

Salve — infused oil plus beeswax, roughly 15-20 g wax per 100 mL oil, melted together. Pours into tins and keeps well.

Compress — a strong infusion on a cloth, for irritated skin.

Tea — drinkable but the internal evidence is much weaker than the topical.

Cream — infused oil with a little emulsifying wax and water for a cosmetic cream.

Cautions and interactions

When this is not a self-care problem — get help

Related

Sources

  1. Homeopathic medicines for adverse effects of cancer treatments. The Cochrane database of systematic reviews 2009; doi:10.1002/14651858.CD004845.pub2 PubMed 19370613
  2. A systematic review of Calendula officinalis extract for wound healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2019; doi:10.1111/wrr.12737 PubMed 31145533
  3. The prevention and management of acute skin reactions related to radiation therapy: a systematic review and practice guideline. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2006; doi:10.1007/s00520-006-0063-4 PubMed 16758176
  4. Bao Yuan Gao vs. Calendula cream for radiotherapy-induced skin toxicity in head and neck cancer: A randomized controlled trial. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2025; doi:10.1016/j.radonc.2025.110976 PubMed 40480289
  5. Efficacy of topical Calendula officinalis on prevalence of radiation-induced dermatitis: A randomised controlled trial. The Australasian journal of dermatology 2021; doi:10.1111/ajd.13434 PubMed 32965030