Fenugreek and milk thistle have low-quality trials. Latch and positioning fix most supply problems.
The evidence on galactagogues is weak, and the most common cause of perceived low supply is not a pharmacological problem.
Most low-supply concerns are position and latch. If the baby is not transferring milk effectively, supply falls because supply is driven by demand. A lactation consultant can assess this in person, and it is the intervention with the best evidence. This is the right first step and it is under-used.
Fenugreek is the most-used galactagogue and the trial literature is low quality: where a pooled analysis found an effect it was small and the confidence was low. It is generally well tolerated; side effects include GI upset, and it can lower blood glucose. It can also cause a maple-syrup smell in the mother and the baby.
Milk thistle (silymarin) has a small randomised trial showing an increase in milk production. The evidence is thin.
Domperidone is a prescription dopamine antagonist used as a galactagogue in some countries. It is not without cardiac risk and it is a clinical decision.
What actually helps supply. Frequent and effective milk removal — feeding on demand, and if supplementing, expressing to keep the demand signal. Skin-to-skin contact. Treating pain or a poor latch. Adequate hydration and nutrition. Sleep, which is difficult and matters. And reassurance, because perceived low supply with an adequately growing baby is common and the baby's weight curve is the objective test.
What reduces supply. Anything that suppresses prolactin or is a dopamine agonist — and that includes large doses of some common herbs — plus smoking, alcohol, some medications, and dehydration. Pseudoephedrine reduces supply, which surprises people taking a decongestant.
Mastitis — a red, hot, painful breast with fever and flu-like aching — needs prompt attention and often antibiotics; it can progress to an abscess. Keep feeding or expressing from the affected side, because emptying helps, and see a clinician promptly. A fluctuant lump with high fever suggests an abscess, which needs drainage.
Meta-Analysis2020The Cochrane database of systematic reviews
Interventions for preventing mastitis after childbirth.
There is some evidence that acupoint massage is probably better than routine care, probiotics may be better than placebo, and breast massage and low frequency pulse treatment may be better than routine care for preventing mastitis.
PubMed 32987448 ↗
Meta-Analysis2020The Cochrane database of systematic reviews
Oral galactagogues (natural therapies or drugs) for increasing breast milk production in mothers of non-hospitalised term infants.
Due to extremely limited, very low certainty evidence, we do not know whether galactagogues have any effect on proportion of mothers who continued breastfeeding at 3, 4 and 6 months.
PubMed 32421208 ↗
Meta-Analysis2017Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine
Treatments for Idiopathic Granulomatous Mastitis: Systematic Review and Meta-Analysis.
Surgical managements had high CR rate with relatively low recurrence rate, with or without steroids.
PubMed 28731822 ↗
Meta-Analysis2014The Cochrane database of systematic reviews
Interventions for treating painful nipples among breastfeeding women.
There was insufficient evidence that glycerine gel dressings, breast shells with lanolin, lanolin alone, or the all-purpose nipple ointment significantly improved maternal perceptions of nipple pain.
PubMed 25506813 ↗
Meta-Analysis2012The Cochrane database of systematic reviews
Chinese herbal medicine for endometriosis.
Post-surgical administration of CHM may have comparable benefits to gestrinone but with fewer side effects.
PubMed 22592712 ↗