Most sore throats are viral. Honey, salt and sage are the useful measures, and antibiotics rarely change anything.
Most sore throats are viral, resolve in about a week, and are treated symptomatically. The interesting evidence is that the simple measures work better than the reputation suggests.
Honey has randomised trial evidence for soothing a sore throat and reducing cough, above one year of age. It must not be given to an infant under 12 months.
Sage has small trials for sore throat and pharyngitis, including as a spray, showing reduced pain. Combined with salt in a gargle it is a reasonable household measure.
Salt-water gargle. Soothing and cheap; it does not treat infection and it does reduce discomfort.
Topical anaesthetic sprays and lozenges reduce pain briefly and can sensitise the mouth with repeated use.
Antibiotics. Most sore throats are viral, and even in confirmed streptococcal infection antibiotics shorten the illness by only about a day while carrying the risks of resistance and allergy. Antibiotics are indicated where there is a specific concern: scarlet fever features, a very unwell patient, a high fever with exudate and no cough in a young person, or someone at risk of rheumatic fever or with immunosuppression. That is a clinical decision, not a household one.
The red flags are the point of this page. A sore throat that stops the person swallowing their own saliva, causes drooling, muffles the voice, causes difficulty breathing, or comes with a one-sided severe swelling is a deep neck infection — a peritonsillar abscess or epiglottitis — and it is an emergency. So is a sore throat with a stiff neck and a rash, which suggests meningitis.
Recurrent tonsillitis is assessed for the pattern rather than treated with another rinse — frequent documented episodes are what justify a specialist conversation.
Meta-Analysis2025Rhinology
Budesonide nasal irrigation for chronic rhinosinusitis: a meta-analysis of therapeutic outcomes and safety profile.
BNI demonstrated improved SNOT-22 and LKES scores, with normal post-treatment IOP and cortisol levels, indicating a beneficial impact on CRS while maintaining safety.
PubMed 39729039 ↗
Meta-Analysis2024Intensive & critical care nursing
Effect of peri-intubation non-pharmacological interventions on postoperative laryngeal symptoms: A systematic review with meta-analysis and meta-regression.
Pre-intubation non-pharmacological interventions were found to be the most effective in reducing the incidence and severity of POST, PEC, and hoarseness.
PubMed 38861781 ↗
Meta-Analysis2021BMJ evidence-based medicine
Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis.
Honey was superior to usual care for the improvement of symptoms of upper respiratory tract infections.
PubMed 32817011 ↗
Meta-Analysis2018The Cochrane database of systematic reviews
Saline irrigation for allergic rhinitis.
Saline irrigation may reduce patient-reported disease severity compared with no saline irrigation at up to three months in both adults and children with allergic rhinitis, with no reported adverse effects.
PubMed 29932206 ↗
Meta-Analysis2016The Cochrane database of systematic reviews
Saline irrigation for chronic rhinosinusitis.
The two studies were very different in terms of included populations, interventions and comparisons and so it is therefore difficult to draw conclusions for practice.
PubMed 27115216 ↗